Fifteen years after murdering his sister on Halloween Night 1963, Michael Myers escapes from a mental hospital and returns to the small town of Haddonfield, Illinois to kill again.
| Loomis | Donald Pleasence |
| Laurie | Jamie Lee Curtis |
| Annie | Nancy Kyes |
| Lynda | P. J. Soles |
| Brackett | Charles Cyphers |
| Lindsey | Kyle Richards |
| Tommy | Brian Andrews |
| Bob | John Michael Graham |
| Marion | Nancy Stephens |
| Graveyard Keeper | Arthur Malet |
| Richie | Mickey Yablans |
| Lonnie | Brent Le Page |
| Keith | Adam Hollander |
| Dr. Wynn | Robert Phalen |
| Michael Myers age 23 | Tony Moran |
| Michael Myers age 6 | Will Sandin |
| Judith Myers | Sandy Johnson |
| Boyfriend | David Kyle |
| Laurie's Father | Peter Griffith |
| The Shape | Nick Castle |
| Dead Mechanic (uncredited) | Barry Bernardi |
| Classmate (uncredited) | Joseph Cornelius |
| Mr. Peter Myers (uncredited) | George O'Hanlon, Jr. |
| Student (uncredited) | Darla Rae |
| Paul (voice) / Michael Myers (uncredited) | John Carpenter |
| Michael Myers (uncredited) | Tommy Lee Wallace |
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