Two sisters move to the country with their father in order to be closer to their hospitalized mother, and discover the surrounding trees are inhabited by Totoros, magical spirits of the forest. When the youngest runs away from home, the older sister seeks help from the spirits to find her.
| Satsuki Kusakabe (voice) | Noriko Hidaka |
| Mei Kusakabe (voice) | Chika Sakamoto |
| Totoro (voice) | Hitoshi Takagi |
| Tatsuo Kusakabe (voice) | Shigesato Itoi |
| Yasuko Kusakabe (voice) | Sumi Shimamoto |
| Granny (voice) | Tanie Kitabayashi |
| Kanta Ogaki (voice) | Toshiyuki Amagasa |
| Kanta's Mother (voice) | Yuko Maruyama |
| Kanta's Father (voice) | Masashi Hirose |
| Kanta's Aunt (voice) | Reiko Suzuki |
| Teacher (voice) | Machiko Washio |
| Catbus (voice) | Naoki Tatsuta |
| Postman (voice) | Tomohiro Nishimura |
| Michiko (voice) | Chie Koujiro |
| Ryoko (voice) | Yuko Mizutani |
| Additional Voices (voice) | Shigeru Chiba |
| Additional Voices (voice) | TARAKO |
| Additional Voices (voice) | Mitsuko Ishida |
| Additional Voices (voice) | Daiki Nakamura |
| Additional Voices (voice) | Akiko Hiramatsu |
| Additional Voices (voice) | Ikue Otani |
