John Anderton is a top 'Precrime' cop in the late-21st century, when technology can predict crimes before they're committed. But Anderton becomes the quarry when another investigator targets him for a murder charge.
| Chief John Anderton | Tom Cruise |
| Agatha | Samantha Morton |
| Danny Witwer | Colin Farrell |
| Director Lamar Burgess | Max von Sydow |
| Lara Clarke | Kathryn Morris |
| Jad | Steve Harris |
| Fletcher | Neal McDonough |
| Knott | Patrick Kilpatrick |
| Dr. Solomon Eddie | Peter Stormare |
| Evanna | Jessica Capshaw |
| Wally the Caretaker | Daniel London |
| Dr. Iris Hineman | Lois Smith |
| Gideon | Tim Blake Nelson |
| Greta van Eyck | Caroline Lagerfelt |
| Rufus Riley at Cyber Parlor | Jason Antoon |
| Leo Crow | Mike Binder |
| Howard Marks | Arye Gross |
| Sarah Marks | Ashley Crow |
| Donald Doobin | Joel Gretsch |
| Casey | Anna Maria Horsford |
| Lamar Burgess' Secretary | Sarah Simmons |
| Chief Justice Pollard | George D. Wallace |
| Dr. Katherine James | Ann Ryerson |
| Older Sean | Tyler Patrick Jones |
| Younger Sean | Dominic Scott Kay |
| Anne Lively | Jessica Harper |
| Pre-Crime Cop | Frank Grillo |
| Pre-Crime Cop | Richard Coca |
| Pre-Crime Cop | Keith Campbell |
| Pre-Crime Cop | Kirk B.R. Woller |
| Pre-Crime Cop | Klea Scott |
| John Doe | Bertell Lawrence |
| Jad's Technician | Eugene Osment |
| Office Worker | James Henderson |
| Office Worker | Vené L. Arcoraci |
| Employee | Erica Ford |
| Tour Guide | Keith Flippen |
| Kid Tourist | Nathan Taylor |
| Technician | Radmar Agana Jao |
| Technician | Karina Logue |
| Technician | Elizabeth Anne Smith |
| Technician | Victoria Garcia-Kelleher |
| Technician | Jim Rash |
| Jucket - Agent #1 | Stephen Ramsey |
| Paymen - Agent #2 | Tom Choi |
| Price - Agent #3 | Tom Whitenight |
| Foley - Agent #4 | William Morts |
| Arthur | Michael Dickman |
| Dashiell | Matthew Dickman |
| Cyber Parlor Customer | William Mesnik |
| Conceited Customer | Franklin Scott |
| Skiing Customer | Severin Wunderman |
| Homeless Person | Max Trumpower |
| Hamburger Mom | Allie Raye |
| Hamburger Dad | Rocael Leiva |
| Homework Boy | Nicholas Edwin Barb |
| Tenement Snitch | Catfish Bates |
| Man | Danny Parker-Lopes |
| Woman | Vanessa Cedotal |
| Mother | Katy Boyer |
| Child | Adrianna Kamosa |
| Child | Kari Gordon |
| Child | Elizabeth Kamosa |
| Child | Raquel Gordon |
| Child | Laurel Kamosa |
| Old Woman | Fiona Hale |
| Violent Wife | Pamela Roberts |
| Husband | Clement Blake |
| Grandfather | Jerry Perchesky |
| Attorney General Nash | Victor Raider-Wexler |
| Celeste Burgess | Nancy Linehan Charles |
| Reporter | Nadia Axakowsky |
| Reporter | Dude Walker |
| Reporter | Tony Hill |
| Reporter | Drakeel Burns |
| Hotel Clerk | William Mapother |
| Paperboy | Morgan Hasson |
| Marks' Son | Andrew Sandler |
| Contortionist | Bonnie Morgan |
| Murder Bystander | Kathi Copeland |
| Murder Bystander | Ana Maria Quintana |
| Murder Bystander | Lucille M. Oliver |
| Murder Bystander | Gene Wheeler |
| Gap Girl | Tonya Ivey |
| Lycon - Seller of Black Inhalers | David Stifel |
| Adulation #1 | Kurt Sinclair |
| Adulation #2 | Rebecca Ritz |
| Adulation #3 | Beverly Morgan |
| Adulation #4 | John Bennett |
| Adulation #5 | Maureen Dunn |
| Adulation #6 | Ron Ulstad |
| Pre-Crime Public Service Announcer | Blake Bashoff |
| Pre-Crime Public Service Announcer | David Doty |
| Pre-Crime Public Service Announcer | Gina Gallego |
| Pre-Crime Public Service Announcer | David Hornsby |
| Pre-Crime Public Service Announcer | Anne Judson-Yager |
| Pre-Crime Public Service Announcer | Meredith Monroe |
| Pre-Crime Public Service Announcer | Benita Krista Nall |
| Pre-Crime Public Service Announcer | Shannon O'Hurley |
| Pre-Crime Public Service Announcer | Jorge-Luis Pallo |
| Pre-Crime Public Service Announcer | Elizabeth Payne |
| Revo Sunglass Model | Ethan Sherman |
| AMEX Polynesian Woman | Jarah Mariano |
| Guinness Man | Miles Dinsmoor |
| Bulgari Model | Vanessa Asbert |
| Bus Passenger (uncredited) | Paul Thomas Anderson |
| Bus Passenger (uncredited) | Cameron Crowe |
| Bus Passenger (uncredited) | Cameron Diaz |
