In 1933 New York, an overly ambitious movie producer coerces his cast and hired ship crew to travel to mysterious Skull Island, where they encounter Kong, a giant ape who is immediately smitten with the leading lady.
| Ann Darrow | Naomi Watts |
| Jack Driscoll | Adrien Brody |
| Carl Denham | Jack Black |
| Kong / Lumpy | Andy Serkis |
| Preston | Colin Hanks |
| Captain Englehorn | Thomas Kretschmann |
| Jimmy | Jamie Bell |
| Bruce Baxter | Kyle Chandler |
| Hayes | Evan Parke |
| Choy | Lobo Chan |
| Herb | John Sumner |
| Mike | Craig Hall |
| Venture Crew | Peter McKenzie |
| Manny | William Johnson |
| Weston | David Pittu |
| Harry | Mark Hadlow |
| Maude | Geraldine Brophy |
| Taps | David Dennis |
| Zelman | Pip Mushin |
| Thuggish Executive | Jim Knobeloch |
| Sleazy Executive | Ric Herbert |
| Studio Guy's Assistant | Lee Donahue |
| Young Assistant | Tom Hobbs |
| Fruit Vendor | Tiriel Mora |
| Venture Crew | Jed Brophy |
| Venture Crew | John Wraight |
| Venture Crew | Will Wallace |
| Venture Crew | Frank Edwards |
| Venture Crew | Crawford Thomson |
| Venture Crew | Richard Kavanagh |
| Venture Crew | Stephen Hall |
| Venture Crew | Joe Folau |
| Old Security Guard | Chic Littlewood |
| Hooverville Child | Samuel Taylor |
| Theatre Actor | Lorraine Ashbourne |
| New York Theatre Goer | Laura Surrich |
| NY Child | Katie Jackson |
| Venture Crew | Michael Lawrence |
| Venture Crew - Helmsman | Ray Woolf |
| Venture Crew - Crewman | Eddie Campbell |
| Venture Crew | Greg Smith |
| Laughing Man | Phil Grieve |
| Photographer | Matt Wilson |
| Photographer | Jim McLarty |
| Photographer | Latham Gaines |
| New York Citizen (uncredited) | Camille Keenan |
| Biplane Gunner | Peter Jackson |
| NY Child | Billy Jackson |
| American Soldier (uncredited) | Jack Machiela |
| Biplane Gunner (uncredited) | Frank Darabont |
| Trampled Theatre-Goer | Matt Dravitzki |