In a countryside town bordering on a magical land, a young man makes a promise to his beloved that he'll retrieve a fallen star by venturing into the magical realm. His journey takes him into a world beyond his wildest dreams and reveals his true identity.
| Tristan Thorn | Charlie Cox |
| Yvaine | Claire Danes |
| Lamia | Michelle Pfeiffer |
| Septimus | Mark Strong |
| Primus | Jason Flemyng |
| Captain Shakespeare | Robert De Niro |
| Victoria | Sienna Miller |
| Empusa | Sarah Alexander |
| Mormo | Joanna Scanlan |
| Ditchwater Sal | Melanie Hill |
| Tertius | Mark Heap |
| Secundus | Rupert Everett |
| Sextus | David Walliams |
| Quintus | Adam Buxton |
| Quartus | Julian Rhind-Tutt |
| King | Peter O'Toole |
| Una / Slave Girl | Kate Magowan |
| Bernard | Jake Curran |
| Guard | David Kelly |
| Dunstan Thorn | Nathaniel Parker |
| Ferdy the Fence | Ricky Gervais |
| Skinny Pirate | Dexter Fletcher |
| Humphrey | Henry Cavill |
| Billy | Mark Williams |
| Girl Bernard | Olivia Grant |
| Narrator (voice) | Ian McKellen |
| Young Dunstan Thorn | Ben Barnes |
| Young Scientist | Bimbo Hart |
| Victorian Academic | Alastair MacIntosh |
| Grumpy Customer | Darby Hawker |
| Mr. Monday | Frank Ellis |
| Bishop | Struan Rodger |
| Soothsayer | George Innes |
| Lackey | Grant Burgin |
| Yvaine's Sister | Eliot Sumner |
| Old Pirate | Terry Murphy |
| Receptionist | Geoff Bell |
| New Bishop | Mark Burns |
| Pirate | Rab Affleck |
| Pirate | Carlos Besse Peres |
| Pirate | Elwin 'Chopper' David |
| Pirate | Adam Fogerty |
| Pirate | Jordan Long |
| Pirate | Spencer Wilding |
| Bishop's Assistant | Philip Harvey |
