When Patrizia Reggiani, an outsider from humble beginnings, marries into the Gucci family, her unbridled ambition begins to unravel the family legacy and triggers a reckless spiral of betrayal, decadence, revenge, and ultimately… murder.
| Patrizia Reggiani | Lady Gaga |
| Maurizio Gucci | Adam Driver |
| Aldo Gucci | Al Pacino |
| Rodolfo Gucci | Jeremy Irons |
| Paolo Gucci | Jared Leto |
| Domenico De Sole | Jack Huston |
| Pina Auriemma | Salma Hayek Pinault |
| Silvana Reggiani | Alexia Murray |
| Fernando Reggiani | Vincent Riotta |
| Franco | Gaetano Bruno |
| Paola Franchi | Camille Cottin |
| Nemir Kirdar | Youssef Kerkour |
| Tom Ford | Reeve Carney |
| Jenny Gucci | Florence Andrews |
| Saïd | Mehdi Nebbou |
| Omar | Miloud Mourad Benamara |
| Ivano Savioni | Andrea Piedimonte Bodini |
| Benedetto Ceraulo | Vincenzo Tanassi |
| Max | Mauro Lamantia |
| Alessandra (3 Years Old) | Nicole Bani Sarkute |
| Alessandra (9 Years Old) | Mia McGovern Zaini |
| Alessandra (Teenager) | Clelia Rossi Marcelli |
| Count Sarzana | Pietro Ragusa |
| Reggiani Trucker | Alessandro Pess |
| Reggiani Trucker | Al Mariotti |
| Reggiani Trucker Secretary | Monica Nappo |
| Upper Crust Stiff | Alessandro Piavani |
| Upper Crust Stiff | Marina Occhionero |
| Priest at Wedding | Pierpaolo Palladino |
| Masseuse | Jun Ichikawa |
| Aldo's French Model | Daphne Morelli |
| Sophia Loren | Mădălina Ghenea |
| Chief Tanner | Gjergj Lala |
| Elderly Female Worker | Alessandra Borgia |
| Pretty Young Worker at Tannery | Havana Alfarano |
| Bobby Short | Philippe Boa |
| Maybeline | Ira Fronten |
| Maternity Ward Nurse | Marika De Chiara |
| Karl Lagerfield | Antonello Annunziata |
| Walter | Edouard Philipponnat |
| IRS Man | Nicola Garofalo |
| IRS Man | Daniele De Martino |
| Paolo's Assistant | Beatrice Pelliccia |
| Aldo's Lawyer | Beppe Rosso |
| Federal Court Judge | Jay Natelle |
| Paolo's Model | Johanna Santos |
| Aldo's Squash Opponent | Larry Kapust |
| Stall Street Holder NYC | Livio Beshir |
| Waiter at Aldo's Party | Pietro Pace |
| Clerk | Bianca Nappi |
| Judge Milan Court | Paolo De Giorgio |
| Patrizia's Father | Mario Opinato |
| Waiter (Boeucc) | Gianpiero Pumo |
| Fashion Show Director | Stefano Moretti |
| Anna Wintour | Catherine Walker |
| Richard Avedon | Martino Palmisano |
| Chalet Guest | Eva Moore |
| Chalet Guest | Filippo De Carli |
| Handwriting Specialist | Marco Sincini |
| Tax Cop | Daniele Monterosi |
| St. Moritz Housekeeper | Daniela Macaluso |
| St. Moritz Housekeeper | Alfredo Pea |
| Swiss Border Guard | Dirk Plönissen |
| Galleria Porter | Mimmo Mancini |
| Cop | Eric Alexander |
| Paolo's Accountant | Beniamino Marcone |
| Chief Police Officer | Simone Spinazzè |
| Anna Wintour's Assistant | Fausto Caroli |
| Judge | Bruce McGuire |
| Judge | Loris Loddi |
| Fashionista | Luke Chikovani |
| Fashionista | Alessandro Egger |
| Fashionista | Roger Garth |
| Porter (uncredited) | Andrea Bruschi |
| Fashionista (uncredited) | Dante Alba |
| Gucci Store Shop Assistant | Marta Marenco |
| Aldo Gucci's Chaffeur (uncredited) | Marco Stefanelli |
| Undertaker (uncredited) | Paolo Sena |
