American car designer Carroll Shelby and the British-born driver Ken Miles work together to battle corporate interference, the laws of physics, and their own personal demons to build a revolutionary race car for Ford Motor Company and take on the dominating race cars of Enzo Ferrari at the 24 Hours of Le Mans in France in 1966.
| Carroll Shelby | Matt Damon |
| Ken Miles | Christian Bale |
| Lee Iacocca | Jon Bernthal |
| Mollie Miles | CaitrÃona Balfe |
| Leo Beebe | Josh Lucas |
| Peter Miles | Noah Jupe |
| Henry Ford II | Tracy Letts |
| Enzo Ferrari | Remo Girone |
| Phil Remington | Ray McKinnon |
| Roy Lunn | JJ Feild |
| Charlie Agapiou | Jack McMullen |
| Franco Gozzi | Corrado Invernizzi |
| Don Frey | Joe Williamson |
| Ford Executive - Ian | Ian Harding |
| John Holman | Christopher Darga |
| AJ "Gus" Scussel | Shawn Law |
| Aeronutronics Chief Engineer | Emil Beheshti |
| Bob Bondurant | Darrin Prescott |
| Dan Gurney | Alex Gurney |
| Bruce McLaren | Benjamin Rigby |
| Denny Hulme | Ben Collins |
| Lorenzo Bandini | Francesco Bauco |
| Ludo Scarfiotti | Guido Cocomello |
| Lloyd Ruby | Adam Mayfield |
| Walt Hansgen | Sean Carrigan |
| Celebrity MC - Cloverfield | Lachlan Buchanan |
| Lance Reventlow | Giles Matthey |
| Dieter Voss | Rudolf Martin |
| SCCA Official | Evan Arnold |
| Reporter - Sam | Darin Cooper |
| Ford Secretary #1 | Elizabeth Dement |
| Dr. Granger | Wallace Langham |
| Pit Engineer - Eddie | Jonathan LaPaglia |
| Wayne (Customer) | Brad Beyer |
| Italian Photographer | Ottavio Taddei |
| Agnelli | Giovanni Cirfiera |
| Cool Young Buyer | Wyatt Nash |
| Pilot Private Plane | Drew Rausch |
| Test Driver - Burt | Ward Horton |
| Ford Italian Translator - Gary | Luiggi Debiasse |
| Brumos Executive | Michael Lanahan |
| Bucknum | Tanner Foust |
| Ferrari Pit Chief | Peter Arpesella |
| Ford Executive #2 | Andrew Burlinson |
| Janitor | Lou Beatty Jr. |
| Kid Program Seller | Clement Larue |
| Drunk Man Singing | Olivier Blin |
| Le Mans Official #1 | Marc Forget |
| Le Mans Official #2 | Stéphane Fiorenza |
| Mechanic Ford Advanced Vehicles | Joss Glennie-Smith |
| Reporter - Daytona | Tim Banning |
| Charlie Brockman ABC | Arron Shiver |
| British Commentator | Paul Fox |
| French Commentator | Zack Zublena |
| German Commentator | Aylam Orian |
| Japanese Commentator | Kirt Kishita |
| Ferrari's English Translator | Stefania Spampinato |
| Agnelli Secretary | Gian Franco Tordi |
| Autograph Seeker | Cameron Hennings |
| IRS Employee #1 | James Tappan |
| IRS Employee #2 | Ryan O'Dell |
| Ferrari Lawyer | Mario Di Donato |
| Ferrari Secretary | Bonnie Antonini |
| Ford Secretary #2 | Jenelle McKee |
| Ford Secretary - Grace | Grace Fae |
| Edwin Turley | Jan Munroe |
| Mrs. Henry Ford | Marisa Petroro |
| Ford Exec Sean Reed | Leif Carlgren |
| Production Line Foreman | Jon Francis Ueberroth |
| Ferrari Pit Crew #1 | Camillo Faieta |
| Ford Executive #3 | Steven Ziel |
| Ford Executive #4 | Vernon Dew |
| Ferrari Pit Crew #2 | Angelo Dibello |
| Shelby Pit Crew - Ronnie Larson | Larsen Deane |
| Shelby Pit Crew - Frosty | Craig Frosty Silva |
| Shelby Pit Crew | Brad McCabe |
| Chris Amon | Brent Pontin |
| Shelby Pit Smokey | Mark Krenik |
| Shelby Pit Big Mug | Thomas John Rudolph |
| Le Mans Flower Girl | Emmeline Luka Bale |
| Claudia Cardinale (uncredited) | Bridie Latona |