A lifelong love of flight inspires Japanese aviation engineer Jiro Horikoshi, whose storied career includes the creation of the A-6M World War II fighter plane.
| Jiro Horikoshi (voice) | Hideaki Anno |
| Honjô (voice) | Hidetoshi Nishijima |
| Naoko Satomi (voice) | Miori Takimoto |
| Kurokawa (voice) | Masahiko Nishimura |
| Castorp (voice) | Stephen Alpert |
| Giovanni Battista (voice) | Mansai Nomura |
| Hattori (voice) | Jun Kunimura |
| Kayo Horikoshi (voice) | Mirai Shida |
| Mrs. Kurokawa (voice) | Shinobu Otake |
| Satomi (voice) | Morio Kazama |
| Jirô's mother (voice) | Keiko Takeshita |
| German Security Guard / Flight Engineer (voice) | Sascha |
| Young Jiro Horikoshi (voice) | Kaichi Kaburagi |
| Young Kayo Horikoshi (voice) | Maki Shinta |
