In the near future, a weary Logan cares for an ailing Professor X in a hideout on the Mexican border. But Logan's attempts to hide from the world and his legacy are upended when a young mutant arrives, pursued by dark forces.
| Logan / X-24 | Hugh Jackman |
| Laura | Dafne Keen |
| Charles | Patrick Stewart |
| Gabriela | Elizabeth Rodriguez |
| Pierce | Boyd Holbrook |
| Caliban | Stephen Merchant |
| Dr. Rice | Richard E. Grant |
| Macon | Stephen Dunlevy |
| Will Munson | Eriq La Salle |
| Kathryn Munson | Elise Neal |
| Nate Munson | Quincy Fouse |
| Federale Commander | Al Coronel |
| Federale Lieutenant | Frank Gallegos |
| Federale | Anthony Escobar |
| Rey | Reynaldo Gallegos |
| Mohawk | Krzysztof Soszynski |
| Bone Breaker | Daniel Bernhardt |
| Pretty Boy | Ryan Sturz |
| Reaver | Jef Groff |
| Reaver | Brandon Melendy |
| Reaver | Oren Hawxhurst |
| Reaver | Jeremy Fitzgerald |
| Reaver | Chris Palermo |
| Reaver | Paul O'Connor |
| Reaver | Clinton Roberts |
| Reaver | Rocky Abou-Sakher |
| Reaver | Keith Jardine |
| Reaver | Jean Claude Leuyer |
| Reaver | Andrew Arrabito |
| Reaver | Sebastian James |
| Reaver | Aaron Matthews |
| Reaver | Garrett Hammond |
| Reaver | Matt McClain |
| Motel Manager | Maureen Brennan |
| Rictor | Jason Genao |
| Rebecca | Hannah Westerfield |
| Bobby | Bryant Tardy |
| Charlotte | Ashlyn Casalegno |
| Delilah | Alison Fernández |
| Lizard Boy | Parker Lovein |
| Mexican Staff Member | Jimmy Gonzáles |
| Convenience Store Clerk | Dave Davis |
| Jackson | Lennie Loftin |
| Bartender | Mark Ashworth |
| Old Doctor | James Handy |
| Prom Teen #1 | Bryce Romero |
| Prom Teen #2 | Phi Vu |
| Prom Teen #3 | Chester Rushing |
| Prom Teen #4 | David Simpson |
| Bridesmaid | Lauren Gros |
| Pastor | John Raymond |
| Mourning Widow | Vanessa Cloke |
| Maria | Doris Morgado |
| Infirmary Nurse | Katie Anne Mitchell |
| Car Dealer | Lara Grice |
| Major | James Moses Black |
| Banger | Ned Yousef |
| Banger | Michael Lehr |
| Banger | Baxter Humby |
| Banger | Bryan Sloyer |
| Banger | Daniel Hernández |
| Federale | John Bernecker |
| Federale | Evan Dane Taylor |
| Federale | Joe Nin Williams |
| Federale | Toby Holguin |
| Federale | Robert Wu |
| Federale | Anthony N. |
| Federale | Victor Winters-Junco |
| Federale | Eyad Elbitar |
| Federale | Craig Henningsen |
| Valet | Han Soto |
| Pine Cone Girl | Rissa Rose Kilar |
| Jonah | Salef Celiz |
| Mutant Child | Aidan Kennedy |
| Mutant Child | Nayah Murphy |
| Mutant Child | Chase Cubia |
| Mutant Child | Emma Teo |
| Mutant Child | Vincenzo Lucatorto |
| Mutant Child | Noell Jellison |
| Mutant Child | Haley Glass |
| Mutant Child | Ella Rowbotham |
| Mutant Child | Hudson Wright |
| Mutant Child | Sebeon Jackson |
| Glowing Eyes Boy | Kelton DuMont |
| Jackson's Henchman | Damon Carney |
| Screaming Casino Woman | Cynthia Woods |
| Bumpy Skinned Kid | Mali O'Connor |
| Rhodes | David Kallaway |
| Border Guard | Robert Vargas |
| Helicopter Pilot | David Paris |
| Special Forces (uncredited) | Gonzalo Robles |
| Reaver (uncredited) | Tim Connolly |
| Bridesmaid (uncredited) | Mary Peyton Stewart |
| Casino Patron (uncredited) | Julia Holt |
| Special Forces Solider (uncredited) | Paul Adkins |
| FBI Agent (uncredited) | Michael Love Toliver |
