Gellert Grindelwald has escaped imprisonment and has begun gathering followers to his cause—elevating wizards above all non-magical beings. The only one capable of putting a stop to him is the wizard he once called his closest friend, Albus Dumbledore. However, Dumbledore will need to seek help from the wizard who had thwarted Grindelwald once before, his former student Newt Scamander, who agrees to help, unaware of the dangers that lie ahead. Lines are drawn as love and loyalty are tested, even among the truest friends and family, in an increasingly divided wizarding world.
| Newt Scamander | Eddie Redmayne |
| Tina Goldstein | Katherine Waterston |
| Jacob Kowalski | Dan Fogler |
| Queenie Goldstein | Alison Sudol |
| Grindelwald | Johnny Depp |
| Albus Dumbledore | Jude Law |
| Credence Barebone | Ezra Miller |
| Leta Lestrange | Zoë Kravitz |
| Theseus Scamander | Callum Turner |
| Nagini | Claudia Kim |
| Seraphina Picquery | Carmen Ejogo |
| Eulalie Hicks | Jessica Williams |
| Yusuf Kama | William Nadylam |
| Grimmson | Ingvar E. Sigurðsson |
| Skender | Ólafur Darri Ólafsson |
| Abernathy | Kevin Guthrie |
| Nicolas Flamel | Brontis Jodorowsky |
| Torquil Travers | Derek Riddell |
| Krall | David Sakurai |
| Minerva McGonagall | Fiona Glascott |
| Spielman | Wolf Roth |
| Bunty | Victoria Yeates |
| Rosier | Poppy Corby-Tuech |
| Arnold Guzman | Cornell John |
| Nagel | Claudius Peters |
| Stebbins | Bart Soroczynski |
| Irma Dugard | Danielle Hugues |
| McClaggan | Alfie Simmons |
| McClaggan's Friend | Isaac Cortinovis Johnson |
| Receptionist | Olivia Popica |
| Child in Bubble | Alfie Mailley |
| Chang | Simon Wan |
| MacDuff | Andrew Turner |
| Credence's Aunt | Linda Santiago |
| Red-Haired Witch | Alfrun Rose |
| Carrow | Maja Bloom |
| Melusine | Olwen Fouéré |
| Krafft | Simon Meacock |
| Portkey Tout | David Wilmot |
| French Policeman | Ed Gaughan |
| Young Grindelwald | Jamie Campbell Bower |
| Young Dumbledore | Toby Regbo |
| Mustafa Kama | Hugh Quarshie |
| Laurena Kama | Isaura Barbé-Brown |
| Corvus Lestrange Senior | Keith Chanter |
| Gryffindor Girl | Jemima Woolnough |
| Gryffindor Girl | Hollie Burgess |
| Young Leta Lestrange (13-16 Years Old) | Thea Lamb |
| Young Newt (13-16 Years Old) | Joshua Shea |
| Yusuf Kama (12 Years Old) | Isaac Domingos |
| Young Leta Lestrange (3-6 Years Old) | Ruby Woolfenden |
| Young Auror-Auditorium | Christopher Birks |
| Mrs. Lestrange (uncredited) | Sabine Crossen |
| Old Carnie (uncredited) | Morrison Thomas |
| Ministry of Magic Witch (uncredited) | Johanna Thea |
| Ministry of Magic Witch (uncredited) | Liv Hansen |
| Ministry of Magic Wizard (uncredited) | Israel Ruiz |
| Senior Wizard (uncredited) | Jag Patel |
| Wizard (uncredited) | Deepak Anand |
| The Rowdy Frenchman (uncredited) | Andrew Blackall |
| Prisoner 001 (uncredited) | Phil Hodges |
| Shopkeeper (uncredited) | Michael Haydon |
| Spectrum (uncredited) | Tim Ingall |
| Cirque Arcanus Worker (uncredited) | Stephen McDade |
| Circus passerby (uncredited) | Jeremy Oliver |
| Muggle at Circus (uncredited) | Dave Simon |
| Chef (uncredited) | Jason Redshaw |
| Doorman (uncredited) | Callum Forman |
| Sailor (uncredited) | Ryan Hannaford |
| Circus Compare (uncredited) | Donna Preston |
| Macusa Prison (uncredited) | Nasir Jama |
| Shafiq (uncredited) | Aykut Hilmi |
| Parisian Woman (uncredited) | Natalie Lauren |
| Muggle (uncredited) | Deano Bugatti |
| Party Guest (uncredited) | Adrian Wheeler |
| Wand Seller (uncredited) | Annarie Boor |
| Teenager in House (uncredited) | Sean Coleman |
| French Muggle (uncredited) | Ana Cilas |
| Cafe Owner (uncredited) | Grant Crookes |
| Amphitheatre Witch (uncredited) | Sarah-Jane De Crespigny |
| Circus Beastmaster (uncredited) | Mike Wood |
| School Pupil (uncredited) | Maddie Evans |
Fantastic Beasts: The Crimes of Grindelwald on Wikipedia
Fantastic Beasts: The Crimes of Grindelwald on IMDb