Elena Houghlin is a scientist, engineer and inventor of Calisto -- a sustainable energy source that will revolutionize the way people use power. It will be ready as soon as she works out the last issue, if not it could be turned into a dangerous weapon. But when the cutting edge technology is pushed to an investor before she can do that, Elena turns to the Townsend Agency for help. Now, it's up to the Angels -- Jane, Sabina, and the newly recruited Elena -- to retrieve Calisto before it can be transformed into a weapon of mass destruction.
| Sabina Wilson | Kristen Stewart |
| Elena Houghlin | Naomi Scott |
| Jane Kano | Ella Balinska |
| Boz | Elizabeth Banks |
| John Bosley | Patrick Stewart |
| Edgar Bosley | Djimon Hounsou |
| Alexander Brok | Sam Claflin |
| Hodak | Jonathan Tucker |
| Peter Fleming | Nat Faxon |
| Jonny Smith | Chris Pang |
| Saint | Luis Gerardo Méndez |
| Langston | Noah Centineo |
| Ralph | David Schütter |
| Ingrid (Angel) | Hannah Hoekstra |
| Passing Woman (Angel) | Jane Chirwa |
| Prince Alim Hassan | Emre Kentmenoğlu |
| Pradeep Prasad | Murali Perumal |
| Sven Ludwig | Sebastian Kroehnert |
| Watchmaker Schmidt | Franz Xaver Zach |
| The Accountant | Andreas Schröders |
| Fatima Ahmed | Marie-Lou Sellem |
| Bettor | Batur Belirdi |
| Susan Olson | Anna Drexler |
| Istanbul Ferry Girl | Tanem Çalbayram |
| NY Bosley | Michael Strahan |
| LA Bosley | Neil Malik Abdullah |
| LA Bosley | Nick Dong-Sik |
| LA Bosley | Dennenesch Zoudé |
| Brok Lobby Security | Peter Sikorski |
| Level 4 Guard | Frederic Böhle |
| Ralph Guard #1 | Eric Bouwer |
| Cyclist | Marco Grahl |
| Model | Livia Matthes |
| Dancer | Tessa Achtermann |
| Dancer | Jabar Werner |
| Dancer | Daria Nowak |
| Dancer | Kiani Del Valle |
| Dancer | Jakob Yaw Yeboah |
| Dancer | Helen Aschauer |
| Charlie (voice) | Robert Clotworthy |
| Kelly Garrett | Jaclyn Smith |
| Driving Instructor | Danica Patrick |
| Fight Instructor | Ronda Rousey |
| Bomb Instructor | Laverne Cox |
| Angel Recruit | Hailee Steinfeld |
| Angel Recruit | Chloe Kim |
| Angel Recruit | Lili Reinhart |
| Angel Recruit | Aly Raisman |
| Angel Recruit | Huda Kattan |
| Big Man (uncredited) | Robert Maaser |
| Party Guest (uncredited) | Nathalie Nailly |
| Angel Recruit (uncredited) | Samantha Hunter Ogan |
| Old Man in Market (uncredited) | Danny Pardo |
| Istanbul Muezin (uncredited) | Anouar H. Smaine |
| Gate Angel (uncredited) | Monique StaTeena |
