A portal transports Cpt. Artemis and an elite unit of soldiers to a strange world where powerful monsters rule with deadly ferocity. Faced with relentless danger, the team encounters a mysterious hunter who may be their only hope to find a way home.
| Artemis | Milla Jovovich |
| The Hunter | Tony Jaa |
| Admiral | Ron Perlman |
| Lincoln | T.I. |
| Marshall | Diego Boneta |
| Dash | Meagan Good |
| Steeler | Josh Helman |
| Axe | Jin Au-Yeung |
| Handler | Hirona Yamazaki |
| Aiden | Jannik Schümann |
| Lea | Nanda Costa |
| Captain Roark | Nic Rasenti |
| JSO V22 Pilot #1 | Clyde Berning |
| JSO Soldier #2 | Paul Hampshire |
| Comms Officer E3 Sentry | Schelaine Bennett |
| Commander West E3 Sentry | Bart Fouche |
| E3 Sentry Pilot | Pope Jerrod |
| Palico | Aaron Beelner |
| Hunter #2 | Adrián Muñoz |
