Op and Ed, two adorable donut-shaped animals - flummels - accidentally time-travel from 1835 to modern-day Shanghai. There they discover traffic, trans fats, and worst of all, that flummels are now extinct. It's up to this bumbling pair to save themselves and their species...and, just maybe, change the course of history.
| Ed (voice) | Adam Devine |
| Op (voice) | Rachel Bloom |
| Dottie (voice) | Zazie Beetz |
| Clarance (voice) | Ken Jeong |
| Burnie (voice) | Jim Jefferies |
| Alma (voice) | Catherine O'Hara |
| Hoss / Ernest Shackleton (voice) | Reggie Watts |
| Jepson (voice) | Henry Winkler |
| Mali (voice) | Alex Borstein |
| Dr. Chung (voice) | Benedict Wong |
| Mrs. Sun / Little Girl (voice) | Julia Chan |
| Charles Darwin (voice) | Tom Hollander |
| Wally (voice) | Richard Kind |
| Vinny (voice) | Steve Aoki |
| Captain (voice) | Nick Frost |
| Conch (voice) | Jon Lovitz |
| Bo (voice) | Sydney Liu |
| Bo's Mom (voice) | Maria Bamford |
| That Guy / Booby (voice) | Raymond S. Persi |
| Bomb (voice) | Terry Gross |
| Cyclops / Donut Store Clerk (voice) | David Silverman |
| News Reporter (voice) | Kelly Hu |
| Mozart / Sled Dogs (voice) | Tom Kenny |
| Narrator / Sled Dogs (voice) | Jason Hightower |
| Sled Dogs (voice) | Kevin Michael Richardson |
| Baseball Announcer (voice) | Brenden P. Hill |